#4292 PATIENT-REPORTED MENTAL HEALTH PROBLEMS, SUICIDE IDEATION, AND CLINICAL OUTCOMES IN ADULTS WITH NON-DIALYSIS CKD: RESULTS OF THE KNOW-CKD STUDY

Abstract Background and Aims Mental health is important for well-being at every stage of life disease. problems are common bothersome in chronic kidney disease (CKD). CKD poorly understood evaluated. To address the importance mental CKD, we analyzed a prospective cohort database from cohort. Method We 1897 participants KNOW-CKD evaluated 4 items as indicators patient-reported health: sleep duration, perceived stress, depressive symptoms, suicidal ideation. facilitate interpretation measure scaled effect size (ES) Kidney Disease Quality Life Short Form (KDQOL-SF) differences among groups problems. investigated association between clinical outcomes incident end-stage (ESKD) all-cause death non-dialysis CKD. Results The mean age was 53 ± 12 years 62% were male. had inadequate duration (17.4%), subject distress (27.3%), experience depression (13.2%), suicide ideation (16.8%), but not well taken care (psychiatric counselling 1.9%, antidepressant therapy 2.8%). item showed large between-groups KDQOL component summary (ES = 1.67). In fully adjusted Cox proportional model, poor (≥2 problems) associated with high risk ESKD [HR 1.46; 95% CI (1.18∼1.08)] 1.55; (1.04∼2.32)] compared to good (no problems). Among health, most predictive indicator outcomes. Conclusion problem undertreated Poor single question significantly death. It suggests that evaluation management